Are there any tests currently available to identify genetic mutations associated with LE?
These types of questions can be very difficult to answer and the responses to individual patients are likely to be somewhat different, depending on the particular situation and the information available. The first thing to think about is the type of lymphedema the patient presents. In Question 1, the young woman could have either primary or secondary lymphedema of her legs. Obtaining a good history, particularly with inquiries about any other family members with lymphedema, performing a thorough clinical evaluation, and obtaining lymphatic imaging usually will provide adequate information. If the lymphedema is secondary, there will be no genetic basis for passing on lymphedema to her offspring. However, she still could have a yet unknown genetic risk for lymphedema, e.g. inadequate levels of lymphatic pro-growth factors that could be passed on to her offspring and may predispose them to secondary LE. If the lymphedema is primary, then we can look at Questions 1 and 2 together. The next
Related Questions
- Provisional Statements Q: What happens as far as provisional statements are concerned (ie what we currently call provisional licences)? What is the associated fee?
- Are there any tests currently available to identify genetic mutations associated with LE?
- Are there other state-led multi-state tests currently being used?
