Are there any studies comparing the different MS/MS search engine results inside or outside of Scaffold?
Yes, here is a list of studies comparing search engine algorithms: Resing KA, Meyer-Arendt K, Mendoza AM, Aveline-Wolf LD, Jonscher KR, Pierce KG, Old WM, Cheung HT, Russell S, Wattawa JL, Goehle GR, Knight RD, Ahn NG., “Improving reproducibility and sensitivity in identifying human proteins by shotgun proteomics.”, Anal Chem. 2004 Jul 1;76(13):3556-68. Rohrbough J, et al. “Verification of Single-Peptide Protein Identifications by the Application of Complementary Database Search Algorithms”, J Biomolecular Tech 2006 Dec 17(5):327-332 Price T, et al, “EBP, a Program for Protein Identification Using Multiple Tandem Mass Spectrometry Datasets”, Mol Cell Proteomics 2007 Mar;6(3)527-36 Kapp EA, Schutz F, Connolly LM, Chakel JA, Meza JE, Miller CA, Fenyo D, Eng JK, Adkins JN, Omenn GS, Simpson RJ An evaluation, comparison, and accurate benchmarking of several publicly available MS/MS search algorithms: sensitivity and specificity analysis. Proteomics. 2005 Aug;5(13):3475-90. doi: 10.1002/pmi
Related Questions
- Why do different search engines yield different results with the exact same search terms? Is one search engine better than another?
- Are there any studies comparing the different MS/MS search engine results inside or outside of Scaffold?
- How is Blueprint different from a search engine like Google, Yahoo, or MS Live?
