Are there any side effects with Herceptin® (trastuzumab) treatment?
Trastuzumab is a very well-tolerated drug, given weekly or every 3 weeks. It has minimal side effects (chills or fever), and those usually appear only with the first dose. However, there is a 1 percent to 4 percent risk of developing congestive heart failure beyond the first dose. Therefore, routine monitoring of your heart function every few months is recommended, particularly in the early stages of your treatment.