Are there any localized symptoms with Protopic application and, if so, how long do they last?
Some patients have reported a burning or stinging during the first few applications of Protopic. These side effects are generally mild and short lasting in the majority of patients. With Protopic 0.1%, 90% of the skin burning events had a median duration of 15 minutes. Localized symptoms are most common during the first few days of application and typically improve as lesions heal. Although these sensations are uncomfortable, patients should not be alarmed and should continue to use Protopic because the burning or stinging will usually diminish over time. In clinical trials, adverse events rarely resulted in discontinuation of treatment.You should tell your patients that to reduce the chance of burning or stinging, they should apply Protopic to dry skin.
