Are there any interactions between Promethazine and other drugs or foods?
Promethazine and certain other medicines can interact with each other. Tell your healthcare professional about all the medicines you take — including prescription and non-prescription medicines, vitamins, and herbal supplements — especially medicines that affect your brain (such as anti-anxiety medicine, sleeping pills, pain medicines, sedatives, narcotics, antidepressants or tranquilizers), epinephrine, a monoamine oxidase inhibitor (MAOI) (used to treat depression or other mental disorders), and medicines called anticholinergics.