Are there any factors that reduce the effectiveness of NG PDT?
Chemotherapy: As this therapy suppresses the immune system and NGPDT activates it, ideally a patient should allow a period of at least one month after last chemotherapy or until the immune system is strong enough before beginning NGPDT . Radiation or Radio-Therapy: (same as for chemotherapy, above) Surgical procedures / a question of timing! As a result of surgery the growth of neo-vasculature tissue commonly occurs as part of the healing process. Since PDT agents selectively collect in new vessels and cause coagulation of these vessels this is effect is beneficial in reducing the blood supply to cancer tumors but if insufficient time (at least one month) has not lapsed since the last surgery this effect in the area of recent surgery would not be desirable. Antibiotics: Following NGPDT the immune system is activated, so ideally patients should not have medicines which reduce this enhancement of the immune system. There is some evidence antibiotics diminish the immune response so antibi
