Are there any data that correlate patient survival or clinical trials to red cell viability?
DR. HE: Well, no, we don’t have data on that, but we do know that when the red blood cells store longer, and then the survival drops. And we know that, many of the late studies showing that the aged red blood cells also associated with adverse clinical outcomes. So here we give the example, wants to try to say that before a device, or before anticoagulant, for storage of the red blood cells to be on the market, we want to assure that the survival is stored in those–the red cells survive, stored in those bags, will be higher than 75 percent. DR. DI BISCEGLIE: Is that certain? DR. HE: It is not but, however, I can tell you that the 75 percent recovery has been debated in the past, many, many years. In fact, since 1947, that was 60 years ago, Dr. Rose already published his paper saying that when you’re evaluating a new RBC collection bag, or RBC storage, storage in solution, and you want to ensure that more than 70 percent of the red blood cells stored in that device are viable. Okay? An
