Are there any conditions in which Saccharomyces boulardii should not be taken?
S. boulardii is generally well tolerated however few contraindications exist. People with known allergies to Saccharomyces cervisiae should avoid use of S. boulardii. Currently no clinical studies on the safety of S. boulardii during pregnancy are available. Pregnant women should consult a health care professional before use. There have been reports of opportunistic infections in severely immunocompromised patients and in patients with indwelling vascular catheters after supplementation with S. boulardii. In rare cases, people with an indwelling vascular catheter sharing a hospital room with a person taking S. boulardii have developed catheter and blood stream S. boulardii infections. It is likely these catheter and blood infections were related to careless handling of the S. boulardii and poor handwashing by medical staff. S. boulardii should be used with caution in severely immunocompromised patients. People with chronic indwelling vascular catheters should not use S. boulardii.
