Are there any adverse reactions associated with MALARONE?
For prophylaxis: In adults, the most commonly reported adverse events possibly attributable to MALARONE versus placebo were headache (5% vs. 7%) and abdominal pain (3% vs. 5%); in pediatric patients, headache (14% vs. 14%), abdominal pain (31% vs. 29%), and vomiting (7% vs. 6%). MALARONE is contraindicated for prevention of P. falciparum malaria in patients with severe renal impairment (creatinine clearance MALARONE is contraindicated in individuals with known hypersensitivity to atovaquone or proguanil HCl or any component of the formulation. Rare cases of anaphylaxis following treatment with MALARONE have been reported. For complete information on MALARONE, please see the prescribing information.