Are the protein microarrays Invitrogens ProtoArray or some other product?
We’re collaborating with Harvard’s proteomics facility. They have a technique called NAPPA [or Nucleic Acid-Programmable Protein Array]. We’re collaborating with Josh [LaBaer, who had headed the Harvard facility and is now director of Arizona State University’s Biodesign Institute’s Virginia G. Piper Center for Personalized Diagnostics]. We’re actually adapting his method. Have you been able to detect other kinds of interactions aside from the one described in the PNAS paper that you will be following up on? Yes … for example, no one can work with smallpox virus. It’s a very difficult virus to work with; it’s very dangerous, and there are only two places in the world that are allowed to work with live virus. We’re very interested in this family and so we’ve been studying its related family members in two other viruses that we can work with in the laboratory. One of them is a virus called cowpox. Cowpox has a very closely related version of this protein out of smallpox. We’ve deleted th