Are the known cases of C. sordellii infection following medical abortion likely to be an underestimate of what is really happening?
No, the total number of cases of infection reported is very close to the true occurrence of C. sordellii following medical abortion and is not the tip of the iceberg. The report of adverse events following Mifeprex use—through MedWatch, the FDA Safety Information and Adverse Event Reporting Program—is thought to be more complete and accurate than with other drugs because of the restricted distribution of the drug and the mandated reporting system. That is, all physicians who prescribe Mifeprex must sign a Prescriber’s Agreement stating that they will report all serious adverse events to Danco. In contrast, there is no comparable central reporting system for pregnancy-related adverse events or surgical abortion. In addition, any death is more likely to be reported than other adverse events and more likely to be known publicly. Since C. sordellii infections following medical abortion have had a 100% mortality to date, their occurrence is most likely to be reported, investigated, and writ
Related Questions
- Are the known cases of C. sordellii infection following medical abortion likely to be an underestimate of what is really happening?
- Is mifepristone medical abortion more likely to lead to fatal infection than other methods of abortion and pregnancy outcomes?
- Could the process of medical abortion explain the risk of C. sordellii infection?
