Are the Keloid fibroblasts considered cancerous?
The Keloid fibroblasts are not cancerous, but may be considered benign tumor. This is because there are some cancerous characteristics, such as fast proliferation, invasiveness, fast migration, apoptotic genes are down regulated and anti-apoptotic genes are up regulated, etc. • Which cells produce more collagen? Keloid fibroblasts produce approximately 20 times more collagen than normal dermal fibroblasts while aging fibroblasts produce less collagen than young skin fibroblasts. • Which cells are more elastic? Keloid and Hypertrophic Scar cells are less elastic than normal skin cells. • Are the cells tested against potential infectious hazards? The cells are analyzed for HIV, HBV and HCV. However, note that CellResearch’s cell cultures are of human origin and while every effort has been taken to test the cells, no diagnostics tests can ensure the total absence of infectious agents. All cells of human origin should be treated as potential pathogens.
