Are the cold caps uncomfortable?
For about the first five minutes after each cap is put on, the sensation is quite cold. Warm blankets are helpful, and a shoulder massage seems to help as well. The discomfort dissipates after that, and the remaining 25 minutes of wear are comfortable to the point that one can hold a normal conversation or even play cards to pass the time. Of note, even if a patient had chemotherapy without cold cap therapy, his/her body would feel cold because the saline being infused into the blood circulatory system is at ambient (room) temperature, not body temperature. This is why chemo clinics often supply blankets and patients are usually advised to wear sweaters.