Are single or multiple brain metastases more common?
Fifty percent of the time a single metastasis appears in the brain. For the other half of patients, multiple brain metastases occur. Although some brain metastases occur as the first site of metastatic disease, most of the time, they occur later in the course of metastatic breast cancer (and called solitary brain metastases). Generalized swelling, as well as the location of metastases in the brain, determines what physical, mental, or sensory functions will be affected.