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Are serum lipids associated with increased risk of maculopathy?

April 26, 2017associated external eye disease eye increased Lipids maculopathy ophthalmology risk serum visual science

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Are serum lipids associated with increased risk of maculopathy?

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There has been considerable study of the risk factors for the development of diabetic retinopathy. In both type 1 and type 2 diabetic subjects, duration of diabetes,3 glycaemic control,11,12 presence of hypertension and nephropathy13 have been associated with increased risk of retinopathy. There has been interest in the link between serum lipids and retinal exudates for 40 years.14 A number of cross-sectional studies suggest that serum lipids may have a causative role in the development of macular exudates. Comparison of a small group of diabetic patients with severe exudative maculopathy to a group with non-exudative retinopathy demonstrated a significantly higher level of serum triglyceride in the former group, although serum cholesterol was not significantly different.15 A case control study (n = 26) where patients were matched for age, gender, glycaemic control, duration and treatment of diabetes, found a trend for patients with maculopathy to have higher serum lipids over 7 years’

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There has been considerable study of the risk factors for the development of diabetic retinopathy. In both type 1 and type 2 diabetic subjects, duration of diabetes,3 glycaemic control,11,12 presence of hypertension and nephropathy13 have been associated with increased risk of retinopathy. There has been interest in the link between serum lipids and retinal exudates for 40 years.14 A number of cross-sectional studies suggest that serum lipids may have a causative role in the development of macular exudates. Comparison of a small group of diabetic patients with severe exudative maculopathy to a group with non-exudative retinopathy demonstrated a significantly higher level of serum triglyceride in the former group, although serum cholesterol was not significantly different.15 A case control study (n = 26) where patients were matched for age, gender, glycaemic control, duration and treatment of diabetes, found a trend for patients with maculopathy to have higher serum lipids over 7 years’