Are plasma concentrations of leptin and carnitineinterrelated in haemodialysis patients?
1 Department of Nephrology, Endocrinology and Metabolic Diseases, Silesian University Medical School, Katowice, 2 Department of Clinical Nutrition and 3 Department of Nephrology, Medical University of Gdask, Poland Sir, Recently a novel form of lipolysis in adipocytes stimulated by leptin was described in Zucker diabetic rats [1]. In this form of lipolysis, leptin increases release of glycerol without the parallel proportional rise in free fatty acids. Carnitine is a coenzyme of carnitine palmitoyl transferase-1, which controls the transport of long-chain fatty acids into mitochondria where oxidation of fatty acids takes place [2]. An upregulation of carnitine palmitoyl transferase-1 and acyl CoA oxidase mRNA was shown . . .
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