Are people who have higher tryptase levels sicker?
On average, I would say that the greater the mast cell burden, the more problems a person is going to have, but this disease affects different people very differently. It’s dangerous to make a generalization because usually three people will pop up to tell you that you don’t know what you’re talking about! There are people out there, walking around, who have full-blown systemic mastocytosis and don’t even know it. In other words, there are people with increased mast cell burdens who don’t really have enough symptoms to go see a doctor about them!
