Are particular families more at risk of pregnancy-related complications?
You are probably aware that HHT affects members of you family in different ways, even though everyone with HHT in any one particular family will have the same genetic defect. This suggests that factors other than the mutated gene contribute to how HHT develops in any one individual, and this includes pregnancy-related complications. When we looked at a series of 161 HHT pregnancies, 11 women had significant complications. Importantly, all except one of these women had close female relatives who had successful, uncomplicated pregnancies. The women belonged to eight different HHT families, with different genetic mutations, and there appeared to be nothing special about these families. So just because a family member has or has not suffered a complication does not mean that the same will happen to you. HHT Pregnancy: The Facts Will the baby be all right? Two published reports have now shown that the miscarriage rate is comparable in HHT and non-HHT pregnancies. Obviously, on average, one-
