Are newly made proteins transported to the smooth endoplasmic reticulum for further processing?
endoplasmic reticulum. Those released into the cytoplasm may make their way into the nucleus if they have the nuclear localisation signal. Proteins that contain an N terminal signal sequence in their amino acid sequence will be transported into the rough endoplasmic reticulum or the RER membrane, where they will undergo further processing (mainly glycosylation) before vesicular transport to an organelle or the cell membrane.
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