Are liposomes harmful?
Quite different are fluid nanoparticles and their hydrophilic relatives, the liposomes. They penetrate into the barrier layers of the horny layer where they dissolve immediately due to their specific composition. During this process a fluidization of the skin barrier layers takes place and the encapsulated active agents are released and can pass through the skin barrier. A specific advantage of fluid nanoparticles is that besides lipophilic active agents, natural oils can be forced into a sensorial agreeable aqueous dispersion without adding synthetic or barrier disturbing emulsifiers (which easily penetrate into the skin and can cause irritation). With all the commotion about small particles it should always be kept in mind that the skin is continuously exposed to substances the size of molecules. Depending on their size and polarity they more or less pass through the skin barrier or are completely retained. Small molecules occur in sizes less than 1nm (nanometre). Atoms and ions, abo