Are insulin levels and Ghrelin level connected in the body?
Other researchers report that insulin plays a role in regulating ghrelin levels. Ghrelin levels were monitered in 8 non-diabetic adults as they were given a 2-hour infusion of insulin. Shortly after the infusion began, levels of ghrelin began to drop. When the insulin infusion was stopped, levels of the hunger hormone began to rise and rapidly returned to normal. Since insulin is already known to increase levels of leptin — the “obesity hormone” that is thought to tell the brain to curb appetite after eating — the findings suggest that insulin plays an important role in controlling what we eat. Ghrelin represents one of the most promising breaking targets in the field of obesity. Although scientists only identified ghrelin in 1999, more than 200 papers on the substance have already been published. Ghrelin acts to stimulate food intake but blood levels are reduced in obese patients suggesting that this mediator represents a key regulator of food intake.
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