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Are children with Alagille syndrome at risk for developing a heart attack later in life due to their high cholesterol?

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Are children with Alagille syndrome at risk for developing a heart attack later in life due to their high cholesterol?

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It is well known that high cholesterol in adults increases the risk of developing heart disease. The impact of high cholesterol in children with Alagille syndrome on their risk of heart attack later in life is not known though it has not been observed to be a problem. Families often ask about putting their children on statin drugs which are used to lower cholesterol in adults. These should be used cautiously because they can cause liver problems.

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