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Are BSCs and CACIs that re-circulate air within a room after filtering through HEPA filters (versus venting to the outside) completely prohibited in the revised USP 797 standard?

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Are BSCs and CACIs that re-circulate air within a room after filtering through HEPA filters (versus venting to the outside) completely prohibited in the revised USP 797 standard?

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When preparing hazardous drugs, the answer is yes. All BSC’s CACI’s must be vented to the outside. Utilization of re-circulating BSC’s or CACI’s for non-hazardous CSI preparation is acceptable.

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