Are artemisinin derivatives safe to use in pregnant women?
There are limited reports on the use of artemisinin and its derivatives during pregnancy. Currently, the World Health Organization (WHO) recommends the use of artemisinin derivatives in pregnant women with severe malaria. Additionally, they are recommended for use in pregnant women with uncomplicated malaria in the second and third trimester of pregnancy in areas of multiple drug resistance. Due to a lack of data, the use of artemisinin derivatives in the first trimester of pregnancy is not recommended.