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Are anti-angiogenesis drugs ever combined with other chemotherapy drugs?

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Are anti-angiogenesis drugs ever combined with other chemotherapy drugs?

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There is some reason to believe that standard chemotherapy drugs and anti-angiogenesis drugs may work well in combination. In early clinical trials of bevacizumab (Avastin), it was determined that bevacizumab alone did not help cancer patients live longer. In subsequent studies, however, it was found that when combined with other chemotherapy drugs it was more effective.

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