Are Acetyl-L-Carnitine And Alpha Lipoic Acid Effective In Reducing Neuropathic Pain?
Acetyl-L-carnitine, in the acetylated form of L-carnitine and two compounds, shares similar properties that promote increased energy and increased metabolism. Acetyl-L-carnitine occurs naturally in the body and supports the availability of acetyl-CoA, an important energy generating metabolite. It also supports proper mitochondrial function and cell membrane stability. The acetyl group from acetyl-L-carnitine is an important factor in the production of the neurotransmitter acetylcholine. Researchers have shown that acetyl-L-carnitine, when it is taken in doses of 1,000 mg tid, is efficacious in alleviating pain in patients who have chronic diabetic neuropathy. The clinical data has shown significant improvement in nerve regeneration and vibratory perceptions.34 Alpha lipoic acid, which is also known as thioctic acid, is a natural antioxidant that is both water- and fat-soluble. This powerful antioxidant neutralizes harmful free radicals and enhances the activity of vitamins C and E. Alp
