Among patients with PBA, what is the relative frequency of crying versus laughing versus both?
The consensus among panel members was that crying is a much more common symptom of PBA than is laughing. One panel member with >20 years of clinical experience reported that he had in the week prior to the roundtable meeting seen only his second patient (one with a traumatic brain injury) with pathological laughing. Another panel member reported seeing only one patient every 1–2 years with pathological laughing. Panel members caring for persons with neurodegenerative dementias reported more experience with laughter as a symptom of PBA, but reiterated that this symptom is seen only occasionally. One panel member reported that in the preceding 5 years, only three patients with dementias had presented with pathological laughter. This experience was echoed by another panel member whose clinic focuses on the care of persons with frontotemporal dementia, and it was reported that episodic irritability, anxiety, and tearfulness were much more common than paroxysms of laughing. Another panel me
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