A pilot study of steroid therapy after emergency department treatment of acute asthma: is a taper needed?
Author(s): Cydulka RK, Emerman CL Affiliation(s): Department of Emergency Medicine, MetroHealth Medical Center, Cleveland, Ohio 44109-1998, USA. Publication date & source: 1998-01, J Emerg Med., 16(1):15-9. Publication type: Clinical Trial; Randomized Controlled Trial The purpose of this study was to determine if there is a difference in early relapse rates between patients receiving an 8-day course of 40 mg/day prednisone and those receiving an 8-day tapering course of prednisone. Furthermore, we wished to determine if one regimen is superior to the other for minimizing adrenal suppression. This was a prospective, randomized, double blind clinical trial conducted in an urban, university-affiliated Level 1 trauma center. All asthmatic patients with exacerbation who were judged well enough for discharge home from the emergency department (ED) were eligible for participation. Patients with a history of chronic obstructive pulmonary disease, congestive heart failure, pneumonia, pneumothor
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