A parent and sibling of mine have PD. What are my chances of developing the disease?
Your family may have a defect in the gene used to regulate alpha synuclein. This gene is called parkin. Mutations in the parkin gene can be detected in up to 50 percent of patients who develop PD before age 40. a blood test can be performed to look for this mutation. The chances of your developing PD may be as high as 25 percent with a parent and a sibling having the disorder.