A 2 to 2½ month survival time difference for docetaxel and prednisone does not sound like a large one. What can taking it mean to me?
These survival time differences can be reported as a median, or as a hazard ratio. The median survival time means that half of the patients live past a particular point in time and half do not. The median survival time measures survival at a given point in time.The hazard ratio is the reduction in the risk of death over time. Although the median survival time of docetaxel treated patients was 18 months, more importantly the reduction in the risk of death in the docetaxel studies over the entire observation period was 20 percent to 24 percent. This is a comparable risk reduction for those patients treated with chemotherapy for metastatic breast or lung cancer. It is very difficult to determine how any individuals will respond to this combination. We’ve still not identified the factors responsible for better survival time with docetaxel treatment. We have seen patients even in the worst of performance statuses respond well and for a long time. Again 17 percent of patients treated with an
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- A 2 to 2½ month survival time difference for docetaxel and prednisone does not sound like a large one. What can taking it mean to me?
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