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• METOPROLOL (noun) The noun METOPROLOL has 1 sense: 1. beta blocker (trade name Lopressor) used in treating hypertension and angina and arrhythmia and acute myocardial infarction; has adverse side effects (depression and exacerbation of congestive heart failure etc.) Familiarity information: METOPROLOL used as a noun is very rare.
