How does Gabapentin Work?
The researchers do not fully understand how Gabapentin works.Gabapentin/Neurontin is related to gamma amino butyric acid (GABA) which is a natural neuro chemical found in the nervous system. What are the side effects of Gabapentin? A major advantage to this drug (in humans) is that is not metabolized by the liver like some of the other AEDs. It also can be used in combination with liver-metabolized anticonvulsants (ie: PB). In dogs, Gabapentin is metabolized partially by the liver and no one is completely sure of the anticonvulsant effects of this metabolite. How effective is Gabapentin? No one knows for sure yet. However, according to one vet, he feels that Gabapentin really seems to work. For a couple of dogs that were given Gabapentin, they were not seizure-free, but improved significantly. Gabapentin must also be given at least three times a day to have effective serum drug concentrations. Are there drawbacks to using Gabapentin? Yes. Gabapentin is rather expensive. The dosage for
