Why does the drug ACTOS cause edema?
Actos activates the sodium tubules in the distal part of the kidney, making you more prone to salt and water retention. To combat this, take Actos at night before you go to bed. You body naturally diuresis at night, and this will help lower the incidence and severity of the edema. Also, cut down on the salt intake. If needed ask your doctor about a distal acting diuretic or potassium sparing diuretic, such as Lozal (Indapamide).
