What is an erythropoietin test?
Definition Erythropoietin, also called EPO, is a type of protein called a glycoprotein that is formed mainly in the kidneys to stimulate the production of red blood cells. Purpose The erythropoietin (EPO) test is used to determine if hormonal secretion is causing changes in the red blood cells. The test has great value in evaluating low hemoglobin (anemia), and another disorder called polycythemia, in which unusually large numbers of red blood cells are found in the blood. The EPO test is also used to identify kidney tumors and identify or assess kidney disease It also may be used to evaluate abuse by athletes who believe commercially prepared erythropoietin enhances performance. Precautions Not every laboratory is equipped to evaluate EPO, so the reference laboratory (a large commercial lab that does tests for hospitals not equipped to do them) performing the test may require as many as four days to complete the analysis. It should also be noted that EPO values increase in pregnancy,