What are the studys findings?
A. The following findings show disease risks of estrogen-alone use compared to placebo. The number of cases given represent an average for every 10,000 women each year: • Fatal and non-fatal strokes. Increased risk–12 cases more (44 cases in those on estrogen alone and 32 in those on placebo). • Venous thrombosis (blood clot, usually in one of the deep veins of the legs). Increased risk–6 cases more (21 cases in those on estrogen alone and 15 in those on placebo). • Coronary heart disease. No significant difference in risk (neither increased nor decreased)–5 fewer cases (49 cases in those on estrogen alone and 54 in those on placebo). • Colorectal or total cancer. No significant differences in risk (neither increased nor decreased)–1 more case for colorectal cancer and 7 fewer cases for total cancer (for colorectal cancer, 17 cases in those on estrogen alone and 16 in those on placebo; for total cancer, 103 cases in those on estrogen alone and 110 in those on placebo). • All deaths
