Can I image lipid rich structures with WETSEM® technology?
WETSEM® technology allows analysis of lipid structures in an unperturbed state. The ability to image wet samples with SEM avoids the problem of lipid extraction that occurs due to dehydration with organic solvents during lipid imaging with conventional techniques. Many lipid structures are visualized without any enhancement. If staining is required, Osmium tetroxide is well suited for lipids; for detailed protocols, see the QX-102 User Manual.