Should nucleic acid tests (direct virus tests) for HIV, HBV, and HCV be used as initial, screening tests for recipients of BTS tissues?
No. Most nucleic acid tests (e.g. PCR assays) that are used by clinical laboratories are not intended to screen patients for disease, but are FDA-approved to confirm the results of screening tests or to monitor virus activity in patients who are known to have the disease. These tests should not be used in place of the antibody tests recommended here.
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