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What is Asacol?

April 26, 2017asacol

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What is Asacol?

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Mesalamine, USA; Mesalazine, Europe : Asacol is essentially “Azulfidine without the sulfa”. The Asacol formulation of 5-ASA places 5-ASA in an acrylic resin coating which dissolves at pH greater than 7. The tablets are then able to pass through the stomach and upper ileum before the coating is dissolved, releasing the drug in the terminal ileum and colon where the pH is typically greater than 7. Asacol is generally well tolerated. The recommended dose is 2.4 g a day though patients frequently seem to tolerate and benefit from taking up to 4.8 g daily.