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Guidelines for Basic Indoor Air Quality The US EPA, NIOSH and CDC have developed guidelines for maintaining acceptable indoor air quality. · Proper ventilation. Document that ventilation rates are consistent with ASHRAE 62-1999 standards. · Provide acceptable comfort levels for most occupants (ASHRAE 55-1991). · Maintain mechanical equipment and building surfaces in reasonably sanitary condition. · Isolate significant emission sources from occupied spaces. · Control major sources of contamination promptly. · Control humidity and moisture intrusion. · Resolve problems quickly.