How are the investigational vaccines supposed to work?
The vaccine DNA codes for Ebola proteins. After injection, the body should make Ebola proteins for a short time. If this happens, the immune system will be able to make antibodies and cellular immune responses to these proteins. In this way the immune system may recognize and respond quickly to Ebola in the future. Please remember that the vaccines are investigational. We don’t know if they work. The first studies are to see if the vaccines are safe. More testing will be needed eventually to see if vaccinations can prevent Ebola infection.