What are the dermatologic uses of Botox?
The primary uses of Botox are diminishment of facial wrinkles; diminishment of platysmal bands; and treatment of hyperhidrosis. How is Botox handled? BOTOX (100 U) and Dysport are freeze-dried and shipped on dry ice. The product should be kept frozen at -5 C until use (up to 9 months). When preparing for use, the product is gently warmed to room temperature and reconstituted with sterile unpreserved 0.9% saline, with minimal agitation. Some suggest that using preserved saline result in decreased pain on injection. Unused reconstituted Botox should be refrigerated (2-8 C) and used within 4 hours (per manufacturer). In practice, some say that it can be used for 2 days, 2 weeks, and even a month after reconstitution. MYOBLOC does not require reconstitution. It is stable for >30 months (refrigerated) and 9 months at room temperature. How is BOTOX reconstituted? Common dilutions are as follows: Saline (ml) U/0.1 ml 1 10 2 5 2.5 4 5 2 8 1.25 How is BOTOX used? BOTOX is injected using a small
