What causes an abnormal Pap test?
Many abnormal Pap tests are caused by viral infections, such as human papillomavirus (HPV) infection, or other types of infection, such as those caused by bacteria, fungi (yeast), or protozoa (Trichomonas). Natural cervical cell changes (atrophic vaginitis) related to menopause can also cause an abnormal Pap test. Usually cell changes return to normal on their own or after an infection has been treated or has resolved on its own. In some cases, untreated cervical cell changes that cause abnormal Pap tests may progress to precancerous or cancerous stages. Certain high-risk types of HPV, especially types 16 and 18, have been linked to the development of cervical cancer. However, changes in cervical cells usually progress slowly and take many years to become cancer cells.
