What are the unanswered questions?
Among the biggest unanswered questions in the biology of sex in humans one is where do where do females come from. I think the models of how sex differentiation occurs in mammals is extraordinarily male biased. It does a good job of explaining how a testes and a male are produced and models at present actually do a very poor job of explaining how an ovary is formed and how a female develops. That is I think the most obvious hole in our understanding of the development of anatomic differences. Beyond that lie a great many biochemical details that are extraordinary but which at present lie in a big black box that is not in any sense described either in textbooks or even in the primary scientific literature. [There is] the need to unify our understanding of the genetic biological and chemical bases of anatomic differences with our understanding of behavioral differences and our understanding of gender identity, sexual preference, and so on. The fields of sex determination and of gender bi
