Is COPD an inherited disease?
For the majority of people, the answer is no. However, a small percentage of people who lack a particular blood protein—alpha-1 antitrypsin—may pass on a gene for this disease. 1 According to the American Lung Association, the absence of alpha-1 antitrypsin makes emphysema almost inevitable. 4 Those with alpha-1 antitrypsin deficiency who smoke can expect worsening of the disease.