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what is GOA ?

April 26, 2017GOA

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what is GOA ?

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The GOA project aims to provide high-quality Gene Ontology (GO) annotations to proteins in the UniProt Knowledgebase (UniProtKB) and International Protein Index (IPI), and is a central dataset for other major multi-species databases; such as Ensembl and NCBI. GOA has been a member of the GO Consortium since 2001, and is responsible for the integration and release of GO annotations to the human, chicken and cow proteomes. In 2006 GOA became a central participant in the new GOC Reference Genome Annotation project and is committed to the comprehensive annotation of a set of disease-related proteins in human. Because of the multi-species nature of the UniProtKB, GOA also assists in the curation of another 120,000 species. This involves electronic annotation and the integration of high-quality manual GO annotation from all GO Consortium model organism groups and specialist groups (e.g. LifeDB). This effort ensures that the GOA dataset remain a key reference an