Is secretin safe?
In its traditional role, secretin is as safe as any other substance administered in the course of medical investigation. There have been questions raised about repeated administration of secretin coming from pigs (porcine secretin), which may induce an immune response to the substance, but the product currently manufactered by Repligen is synthetic human secretin and should not carry this risk. There have been disturbing reports of seizures occurring during or after secretin infusion in patients who were not previously regarded as being at risk. Two instances of such seizures are reported in the following: trainland.tripod.com/secretin.htm dem0nmac.mgh.harvard.edu/forum_2/AutismF/10.28.997.34AMSeizure.Apn.html [Note from Anna: Like all drugs, it has its risks, but it is important to note that secretin has not been tested in such dosages for use in children. There have been cases of allergic reactions, some of which have been serious (i.e.