How common is hyperhomocysteinemia?
Mild hyperhomocysteinemia levels are seen in about 5%-12% of the general population. In specific populations such as, alcoholics (due to poor vitamin intake) or patients with chronic kidney disease, this may be more common. The severe genetic form, homocystinuria, is rare. How can homocysteine levels be lowered? The consumption of folic acid supplements or cereals that are fortified with folic acid, and to a lesser extent vitamins B6 and B12, can lower blood homocysteine levels. These supplements may even be beneficial in people with mild genetic hyperhomocysteinemia to lower their homocysteine levels. However, it is noteworthy that so far there is no compelling data to support the treatment of hyperhomocysteinemia for prevention of heart disease or treatment of known heart disease or blood clots. There are many studies underway to determine whether there may be any benefit to treat high levels of homocysteine in patients with known heart disease or blood clots. Further recommendations
