What causes GHD?
GHD occurs when the pituitary gland does not make enough GH. This problem may be present at birth, and is the result of the pituitary gland or hypothalamus not functioning normally (also known as hypopituitarism). If GH is the only hormone that is affected, the condition is referred to as isolated GHD. Acquired GHD may be caused by damage to the pituitary at any time after birth. Decreased pituitary gland function leading to GHD may be caused by a brain tumor, cranial and/or spinal radiation treatment for cancer, severe head trauma, infection, or surgical removal of the pituitary gland. Sometimes no specific cause for the GHD can be found.
