What is translational medicine?
Translational medicine or “bench to bedside” research has been defined as: • Non-human or non-clinical studies conducted with the intent to advance therapies to the clinic or to develop principles for application of therapeutics to human disease. • Basic science studies which define the biological effects of therapeutics in humans. • Investigations in humans which define the biology of disease and provide the scientific foundation for development of new or improved therapies for human disease. • Any clinical trial of a therapy that was initiated based on #1–3 with any endpoint including toxicity and/or efficacy.