Does CRINA 20 cause weight gain?
Some women gain weight when they take the Pill. And some lose weight, while others don’t fluctuate at all. Weight can be affected by such a wide range of factors—changes in your lifestyle, diet, exercise routine, or stress level—that it’s hard to pinpoint just one. Bloating, which is caused by water retention, can also give the appearance of weight gain. Drospirenone (DRSP) is the first synthetic progestin to be used in combined oral contraceptives that has antimineralocorticoid properties similar to those of natural progesterone (but more pronounced), and that can counteract the effects of aldosterone. This antimineralocorticoid activity of drospirenone promotes the excretion of excess sodium and water, thus counteracts estrogen-stimulated fluid retention and weight gain.
